Article

Assessing the Performance of Methods for Cell Clustering from Single-cell DNA Sequencing Data

2022-08-15

Abstract excerpt

<h4>Background:</h4> Many cancer genomes have been known to contain more than one subclone inside one tumor, the phenomenon of which is called intra-tumor heterogeneity (ITH). Characterizing ITH is essential in designing treatment plans, prognosis as well as the study of cancer progression. Single-cell DNA sequencing (scDNAseq) has been proven effective in deciphering ITH. Cells corresponding to each subclone are...

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Literature Corpus work: 9720850b-c767-5b50-86a5-adc04212a036
DOI: 10.1101/2022.08.12.503719

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