Article
Comparing algorithms that reconstruct cell lineage trees utilizing information on microsatellite mutations.
PLoS computational biology - 1 Jan 2013
Chapal-Ilani Noa, Maruvka Yosef E, Spiro Adam, Reizel Yitzhak, Adar Rivka, Shlush Liran I, Shapiro Ehud
Abstract excerpt
Organism cells proliferate and die to build, maintain, renew and repair it. The cellular history of an organism up to any point in time can be captured by a cell lineage tree in which vertices represent all organism cells, past and present, and directed edges represent progeny relations among them. The root represents the fertilized egg, and the leaves represent extant and dead cells. Somatic mutations...
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