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A genetically buffered helicase network promotes tolerance of G-quadruplex stabilization in <i>Saccharomyces cerevisiae</i>

2026-07-11

Abstract excerpt

<h4>ABSTRACT</h4> G-quadruplexes (G4s) are non-canonical DNA secondary structures that can impede DNA replication and transcription and provoke genome instability, and DNA helicases of the PIF1 and RecQ families have long been regarded as the principal enzymes that resolve them. To directly test the relative contributions of these families, we measured the growth of Saccharomyces cerevisiae helicase mutants in t...

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Literature Corpus work
b133419e-11bb-5197-a753-07164e69068d
DOI
10.64898/2026.07.07.737069
Open publication

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A genetically buffered helicase network promotes tolerance of G-quadruplex stabilization in <i>Saccharomyces cerevisiae</i>DOI 10.64898/2026.07.07.737069
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