Article

Genome Stability under Silence: DNA Repair Networks in Quiescent Fission Yeast

2025-08-25

Abstract excerpt

<h4>ABSTRACT</h4> Most of our current understanding of genome integrity derives from studies in proliferating cells, yet most somatic cells in multicellular organisms reside in non-dividing, quiescent states. Using Schizosaccharomyces pombe , we dissected the mechanisms by which quiescent cells maintain genome stability in the absence of DNA replication. Combining time-resolved mutational analyses, DNA damage as...

Identifiers and source

Literature Corpus work: 07c9fa18-a2da-5617-90e1-3d0b6ca4c824
DOI: 10.1101/2025.08.24.671962

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