IgGM: A Generative Model for Functional Antibody and Nanobody Design

Abstract excerpt

<h4> A bstract </h4> Immunoglobulins are crucial proteins produced by the immune system to identify and bind to foreign substances, playing an essential role in shielding organisms from infections and diseases. Designing specific antibodies opens new pathways for disease treatment. With the rise of deep learning, AI-driven drug design has become possible, leading to several methods for antibody design. However,...

Topics

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• Amino Acid Sequence
• Antibodies
• Computational Biology
• Germ-Line Mutation
• Glycosylation and Glycoproteins Research
• Monoclonal and Polyclonal Antibodies Research
• Mutation
• Protein purification and stability

Identifiers and source

Literature Corpus work

b09e9781-229d-5ea5-bb06-ebb9e025e2d9

DOI

10.1101/2024.09.19.613838