Article

Accelerating Antibody Design with Active Learning

2022-09-15

Abstract excerpt

<h4>ABSTRACT</h4> Discovering therapeutic antibody starts by screening antibody library of phage-displayed, transgenic mouse or human B cells. The coverage of those kinds of libraries in the entire antibody sequence space is small; thus, the result highly depends on the quality of the library. Exploring sequence space by mutating a template antibody is also impossible to even with the state-of-the-art screening m...

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Literature Corpus work: 74e7a77e-577a-579b-8afc-d82ece10d6d2
DOI: 10.1101/2022.09.12.507690

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