Article
A Generative Foundation Model for Antibody Design
2025-09-16
Abstract excerpt
Antibodies are indispensable components of the immune system, yet the design of high-affinity antibodies remains a time-consuming and experimentally intensive process. To address this challenge, we present IgGM, a novel generative foundation model designed to accelerate high-affinity antibody engineering. IgGM learns the complex relationships underlying the binding interactions between antigens and antibodies, as...
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Identifiers and source
- Literature Corpus work
- 94ad2892-b900-5c2d-92b7-1c0b7321f1dd
- DOI
- 10.1101/2025.09.12.675771