Article

sdAbs-LLM: Generative Large Language Models For <i>de novo</i> Antibody Design and Agentic Evaluation

2026-04-21

Abstract excerpt

<h4>ABSTRACT</h4> Despite major advances in computational antibody engineering, no systematic comparison of modern open-source LLM backbone families for antibody sequence generation exists, nor is it known whether architectural differences matter at compact model scales. In this study, five compact transformer variants inspired by prominent open-source LLM families (Llama-4, Gemma-3, DeepSeek-V3, Mistral 7B, and...

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Literature Corpus work: ec133bae-bed2-5179-87f0-0388b096d2fe
DOI: 10.64898/2026.04.18.716776

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