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Novel antibody language model accelerates IgG screening and design for broad-spectrum antiviral therapy

2024-03-04

Abstract excerpt

Therapeutic antibodies have become one of the most influential therapeutics in modern medicine to fight against infectious pathogens, cancer, and many other diseases. However, experimental screening for highly efficacious targeting antibodies is labor-intensive and of high cost, which is exacerbated by evolving antigen targets under selective pressure such as fast-mutating viral variants. As a proof-of-concept, we...

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Literature Corpus work
e4cbe740-7350-5bfc-a3b6-6717b858362e
DOI
10.1101/2024.03.01.582176
Open publication

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Novel antibody language model accelerates IgG screening and design for broad-spectrum antiviral therapyDOI 10.1101/2024.03.01.582176
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