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Ophiuchus-Ab: A Versatile Generative Foundation Model for Advanced Antibody-Based Immunotherapy

2026-02-04

Abstract excerpt

Antibodies exhibit extraordinary specificity and diversity in antigen recognition and have become a central class of therapeutics across a wide range of diseases. Despite this clinical success, antibody design remains fundamentally challenging. Antibody function emerges from intricate and highly coupled interactions between heavy and light chains, which complicate sequence-function relationships and limit the rati...

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Literature Corpus work
ea716763-5a3d-5b98-9e55-f4ddee1fbe47
DOI
10.64898/2026.02.02.703197
Open publication

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Ophiuchus-Ab: A Versatile Generative Foundation Model for Advanced Antibody-Based ImmunotherapyDOI 10.64898/2026.02.02.703197
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