Article

Generation of antigen-specific paired chain antibody sequences using large language models

2024-12-22

Abstract excerpt

The traditional process of antibody discovery is limited by inefficiency, high costs, and low success rates. Recent approaches employing artificial intelligence (AI) have been developed to optimize existing antibodies and generate antibody sequences in a target-agnostic manner. In this work, we present MAGE (Monoclonal Antibody GEnerator), a sequence-based Protein Language Model (PLM) fine-tuned for the task of ge...

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Literature Corpus work: 370eb7e7-7943-5c6c-85d9-8cd4ea228754
DOI: 10.1101/2024.12.20.629482

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