Article

Deep generative design of neutralizing nanobodies against SARS-CoV-2 variants

2024-10-30

Abstract excerpt

In recent years, single-domain heavy chain antibodies (nanobodies), with only one-tenth the molecular weight of conventional antibodies, have emerged as important therapeutic proteins in the fight against SARS-CoV-2. However, the rapid mutation of the virus often renders existing nanobodies ineffective, underscoring the need to develop nanobodies that specifically target new variants. Traditional methods for disco...

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Identifiers and source

Literature Corpus work: 68876211-83f0-508a-9638-d5295ca89c37
DOI: 10.1101/2024.10.29.620982

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