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Recurrent Stimulation of NK Cell Clones with K562 Expressing Membrane-Bound IL-21 Affects Their Phenotype, IFN-γ Production and Lifespan

2018-12-02

Abstract excerpt

A pattern of NK cell heterogeneity in each individual determines proliferative and functional responses of NK cells to activating stimuli. Obtaining the progeny of a single cell by cloning original population is one of the ways to study the NK cell heterogeneity.  In this work, we used single cell sorting into a plate and stimulation by IL-2 and gene-modified K562 feeder cells expressing membrane-bound IL-21...

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Literature Corpus work
b08de7aa-7953-5fc0-9651-623393fc6b61
DOI
10.20944/preprints201812.0003.v1
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