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Article

Multiple effects of IL-21 on human NK cells in ex vivo expansion

31 Jan 2015

Abstract excerpt

Natural killer (NK) cells (CD56(+)CD3(-)) are large, granular immunocytes that play a very pivotal role in the anti-inflammatory response and tumor surveillance. As an ideal cytotoxic lymphocyte (CTL), NK cells have attracted much attention in clinical trials. However, an insufficient number and their limited life span are bottlenecks that limit the application of NK cells in adoptive immunotherapy. Interleukins...

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PMID: 25758713
DOI: 10.1016/j.imbio.2015.01.009

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