Article

In-vitro Expansion and Transduction of Primary NK Cells Using Feeder Cells Expressing Costimulatory Molecules and IL-21

2024-12-31

Abstract excerpt

<title>Abstract</title> <p>Natural Killer (NK) cells are an important population of the immune system and NK cell-based therapy has been shown great potential in the treatment of cancers. However, to apply NK cells clinically, producing a large number of cells with high cytotoxicity remains a challenge. Current strategies focus on employing different irradiated feeder cells to stimulate NK expansion, maturation,...

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Literature Corpus work: c139de98-2aeb-5a67-af32-2427ec2b462a
DOI: 10.21203/rs.3.rs-5731191/v1

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