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Long-term cytotoxic NK cells with broad anti-tumour capacity proliferate selectively, without exhaustion, after BCG priming and extremely low doses of cytokines

2023-06-07

Abstract excerpt

<h4>Background: </h4> Natural killer (NK) cell-based immunotherapies, currently under investigation, appear to be safe, efficient treatments in patients with haematological tumours. Nevertheless, the short-lived nature of these cells combined with the need to infuse large number of cells for efficient tumour elimination represent important challenges for the development of NK cell-based therapies. Although NK cell...

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Literature Corpus work
c8e4a5c6-ce32-5540-8eb6-1f1132e35042
DOI
10.1101/2023.06.07.543999
Open publication

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Long-term cytotoxic NK cells with broad anti-tumour capacity proliferate selectively, without exhaustion, after BCG priming and extremely low doses of cytokinesDOI 10.1101/2023.06.07.543999
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