Article

Phenotypic and functional characterisation of locally produced natural killer cells ex vivo expanded with the K562-41BBL-mbIL21 cell line

2022-09-21

Abstract excerpt

We characterise the expansion, phenotype and functional activity of natural killer (NK) cells obtained for a clinical trial. Nineteen expansion procedures were performed to obtain NK cell products for 16 patients. NK cells were ex vivo expanded from haploidentical donor peripheral blood mononuclear cells in the presence of the locally generated feeder cell line K-562 with ectopic expression of 4-1BBL and mbIL-21....

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Literature Corpus work: 45470a05-e30b-5739-8fd4-e3a7b06bc95c
DOI: 10.21203/rs.3.rs-1822963/v2

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