Article

In-vitro Expansion and Transduction of Primary Natural Killer Cells Using Feeder Cells Co-expressing Co-stimulatory Receptors and Membrane-bound IL-21

2024-07-25

Abstract excerpt

<title>Abstract</title> <p>Natural Killer (NK) cells are an important population of the immune system and NK cell based therapy shown great potential in the treatment of cancers. However, to apply NK cells clinically, producing a large number of cells with high cytotoxicity remains a challenge. Current strategies focus on employing different irradiated feeder cells to stimulate NK expansion, maturation, and cytot...

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Literature Corpus work: a422639f-4a68-52d0-9c83-80ffe1ed7d9d
DOI: 10.21203/rs.3.rs-4664410/v1

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