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Article

Elucidating the combinatorial effect of substrate stiffness and surface viscoelasticity on cellular phenotype.

Journal of biomedical materials research. Part A - 1 Jun 2022

Chester Daniel, Lee Veronica, Wagner Paul, Nordberg Matthew, Fisher Matthew B, Brown Ashley C

Abstract excerpt

Cells maintain tensional homeostasis by monitoring the mechanics of their microenvironment. In order to understand this mechanotransduction phenomenon, hydrogel materials have been developed with either controllable linear elastic or viscoelastic properties. Native biological tissues, and biomaterials used for medical purposes, often have complex mechanical properties. However, due to the difficulty in completely...

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Identifiers

PMID: 35107204
DOI: 10.1002/jbm.a.37367
PMCID: PMC9305170

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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