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Article

Stiffness-modulated water retention and neovascularization of dermal fibroblast-encapsulating collagen gel.

Tissue engineering. Part A - 1 Jun 2013

Jeong Jae Hyun, Liang Youyun, Jang Michelle, Cha Chaenyung, Chu Cathy, Lee Haekwang, Jung Woonggyu, Kim Jin Woong, Boppart Stephen A, Kong Hyunjoon

Abstract excerpt

There is increasing evidence that matrix stiffness modulates various phenotypic activities of cells surrounded by a three-dimensional (3D) matrix. These findings suggest that matrix stiffness can also regulate dermal fibroblasts activities to remodel, repair, and recreate skin dermis, but this has not yet been systematically demonstrated to date. This study examines the effects of matrix rigidity on the...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 23289622
DOI: 10.1089/ten.TEA.2012.0230
PMCID: PMC3638539

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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