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Transcription factor-based transdifferentiation of human embryonic to trophoblast stem cells

2021-08-18

Abstract excerpt

During the first week of development, human embryos form a blastocyst comprised of an inner cell mass and trophectoderm (TE) cells, the latter of which are progenitors of placental trophoblast. Here we investigated the expression of transcripts in the human TE from early to late blastocyst stages. We identified enrichment of transcription factors GATA2, GATA3, TFAP2C and KLF5 and characterised their protein expres...

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Literature Corpus work
af8421cb-9b91-5581-bda0-9348a5a3b80b
DOI
10.1101/2021.08.18.456785
Open publication

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Transcription factor-based transdifferentiation of human embryonic to trophoblast stem cellsDOI 10.1101/2021.08.18.456785
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