Article

Advancing Human Placental Modeling Through Stem-Cell-Derived Trophoblast Organoids and Reprogramming Innovations

2026-05-22

Abstract excerpt

The human placenta, a transient but vital organ, governs fetal development and maternal-fetal interactions, yet its study has been stymied by ethical and accessibility constraints. Stem cell biology has now revolutionized the capacity to model human placental development, in particular with the derivation of human trophoblast stem cells (hTSCs) and organoids. Classically, hTSCs have been derived from pluripotent s...

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Literature Corpus work: 31a50cdd-550b-5686-a711-a40a123987bf
DOI: 10.20944/preprints202605.1472.v1

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