Article

Pluripotency-Independent Induction of Human Trophoblast Stem Cells from Fibroblasts

2021-11-11

Abstract excerpt

<h4>SUMMARY</h4> Recent studies demonstrated that human trophoblast stem-like cells (hTS-like cells) can be derived from naïve embryonic stem cells or be induced from somatic cells by the pluripotency factors, OSKM. This raises two main questions; (i) whether human induced TSCs (hiTSCs) can be generated independently to pluripotent state or factors and (ii) what are the mechanisms by which hTSC state is establish...

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Literature Corpus work: abfee890-1037-50a7-91cf-0467afe0e1ac
DOI: 10.1101/2021.11.10.468044

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