Article

GATA-regulated transcriptional program dictate cell fate equilibrium to establish the maternal-fetal exchange interface and fetal development

2023-06-22

Abstract excerpt

The placenta establishes a maternal–fetal exchange interface to transport nutrients and gases between the mother and the fetus. Establishment of this exchange interface relies on the development of multinucleated syncytiotrophoblasts (SynT) from trophoblast progenitors and defect in SynT development often leads to pregnancy failure and impaired embryonic development. Here, we show that mouse embryos with condition...

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Literature Corpus work: 5afe63c5-3b37-5089-b4df-9a08ef9bcbf3
DOI: 10.1101/2023.06.19.545618

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