Article

Expression estimation and eQTL mapping for HLA genes with a personalized pipeline

2018-07-10

Abstract excerpt

The HLA (Human Leukocyte Antigens) genes are well-documented targets of balancing selection, and variation at these loci is associated with many disease phenotypes. Variation in expression levels also influences disease susceptibility and resistance, but little information exists about the regulation and population-level patterns of expression due to the difficulty in mapping short reads to these highly polymorphi...

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Literature Corpus work: af6d6764-2060-570c-9679-71f0b5cb9085
DOI: 10.1101/365957

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