Article

Prediction of HLA genotypes from single-cell transcriptome data

2022-06-12

Abstract excerpt

<h4>ABSTRACT</h4> The human leukocyte antigen (HLA) locus plays a central role in adaptive immune function and has significant clinical implications for tissue transplant compatibility and allelic disease associations. Studies using bulk-cell RNA sequencing have demonstrated that HLA transcription may be regulated in an allele-specific manner and single-cell RNA sequencing (scRNA-seq) has the potential to better...

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Literature Corpus work: 0d43e8f8-394e-53e6-8e2d-ca5d02e7ba7c
DOI: 10.1101/2022.06.09.495569

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