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Article

High-throughput, high-fidelity HLA genotyping with deep sequencing.

Proceedings of the National Academy of Sciences of the United States of America - 29 May 2012

Wang Chunlin, Krishnakumar Sujatha, Wilhelmy Julie, Babrzadeh Farbod, Stepanyan Lilit, Su Laura F, Levinson Douglas, Fernandez-Viña Marcelo A, Davis Ronald W, Davis Mark M, Mindrinos Michael

Abstract excerpt

Human leukocyte antigen (HLA) genes are the most polymorphic in the human genome. They play a pivotal role in the immune response and have been implicated in numerous human pathologies, especially autoimmunity and infectious diseases. Despite their importance, however, they are rarely characterized comprehensively because of the prohibitive cost of standard technologies and the technical challenges of accurately...

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Identifiers

PMID: 22589303
DOI: 10.1073/pnas.1206614109
PMCID: PMC3365218

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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