Back to search

Article

<i>Xist</i> expression in male <i>Peromyscus leucopus</i> is associated with restricted chromatin repression and incomplete X-to-autosome dosage compensation

2026-06-15

Abstract excerpt

X-chromosome inactivation (XCI) equalizes X-linked gene dosage between XX females and XY males in eutherian mammals and is canonically initiated by the long noncoding RNA Xist , which coats one X chromosome and recruits Polycomb-mediated chromatin silencing. Xist expression has therefore been considered female-specific and central to balancing gene dosage between two X chromosomes in females and a single X chrom...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work
93b3a0f0-1122-58ee-ac06-c64ad173e74a
DOI
10.64898/2026.06.11.731719
Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest
Interactive article relationship graphSelect a related publication card to move it into the centre and load its closest explainable connections. Solid lines are source-backed structured connections. Dashed lines are semantic discovery signals and are not scientific evidence.
<i>Xist</i> expression in male <i>Peromyscus leucopus</i> is associated with restricted chromatin repression and incomplete X-to-autosome dosage compensationDOI 10.64898/2026.06.11.731719
B cell-specific XIST complex enforces X-inactivation and restrains atypical B cellsSemantic proximity
Mechanistic diversification of <i>XIST</i> regulatory network in mammalsSemantic proximity
Extensive remodelling of <i>XIST</i> regulatory networks during primate evolutionSemantic proximity
X-factors in human disease: impact of gene content and dosage regulation.Semantic proximity
Xist RNA binds select autosomal genes and depends on Repeat B to regulate their expressionSemantic proximity
Dosage compensation and meiotic sex chromosome inactivation are maintained in the absence of selectionSemantic proximity
Elastic dosage compensation by X-chromosome upregulation.Semantic proximity
Low <i>XIST</i> expression in Sertoli cells of Klinefelter syndrome patients caused the high susceptibility of these cells to an extra X chromosomeSemantic proximity
XIST dampens X chromosome activity in a SPEN-dependent manner during early human developmentSemantic proximity
Landscape of X chromosome inactivation across human tissuesSemantic proximity
Single-cell RNA-sequencing reveals pre-meiotic X-chromosome dosage compensation in <i>Drosophila testis</i>Semantic proximity
Dynamics of X chromosome hyper-expression and inactivation in male tissues during stick insect developmentSemantic proximity
Select a neighboring publication to make it the new centre.