Article

Ancestral genomes and population sequencing data reveal strand- and context-specificity of polymorphic G4 sites

2023-09-12

Abstract excerpt

Recent studies highlight the important functional roles of non-canonical DNA conformations. One of such structures, G-quadruplex (G4), was shown to be involved in multiple processes within a cell such as telomere maintenance, gene regulation, protein translation and alternative splicing. On the other hand, DNA in non-double stranded context can hinder replication and repair processes and, indeed, a higher rate of...

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Literature Corpus work: af026117-9215-52d7-994c-6f32a9527fff
DOI: 10.1101/2023.09.08.556792

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