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Article

The disruptive positions in human G-quadruplex motifs are less polymorphic and more conserved than their neutral counterparts.

Nucleic acids research - 1 Sept 2009

Nakken Sigve, Rognes Torbjørn, Hovig Eivind

Abstract excerpt

Specific guanine-rich sequence motifs in the human genome have considerable potential to form four-stranded structures known as G-quadruplexes or G4 DNA. The enrichment of these motifs in key chromosomal regions has suggested a functional role for the G-quadruplex structure in genomic regulation....

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Identifiers

PMID: 19617376
DOI: 10.1093/nar/gkp590
PMCID: PMC2761265

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-19617376-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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