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Article

Global loss of fine-scale chromatin architecture and rebalancing of gene expression during early colorectal cancer development

2022-09-14

Abstract excerpt

<title>Abstract</title> <p>Although 3D genome architecture is essential for long-range gene regulation, the significance of distal regulatory chromatin contacts is challenged by recent findings of low correlation between contact propensity and gene expression. To better understand the role of long-range interactions between distal regulatory elements during the early transformation from healthy colon to colorecta...

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Literature Corpus work
ae90a297-a310-5ec3-815b-314d6c4523bb
DOI
10.21203/rs.3.rs-2003187/v1
Open publication

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Global loss of fine-scale chromatin architecture and rebalancing of gene expression during early colorectal cancer developmentDOI 10.21203/rs.3.rs-2003187/v1
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