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Cardiac muscle-restricted partial loss of Nos1ap expression has limited impact on electro- and echo-cardiographic features

2022-09-28

Abstract excerpt

Genome-wide association studies (GWAS) of QT interval variation have identified common noncoding variants at the NOS1AP gene as the most common genetic regulators of trait variation in the general population. Invoking a cis -regulatory mechanistic hypothesis, we have reported identification of a functional enhancer variant underlying the GWAS signal that influenced human cardiac NOS1AP expression. Functional st...

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Literature Corpus work: ae50e3f3-5e03-554e-be0f-fa810009aaf9
DOI: 10.1101/2022.09.27.509782

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Cardiac muscle-restricted partial loss of Nos1ap expression has limited impact on electro- and echo-cardiographic featuresDOI 10.1101/2022.09.27.509782Read

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Cardiac muscle-restricted partial loss of <i>Nos1ap</i> expression has limited impact on electro- and echo-cardiographic features

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