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Article

Silencing of CCR4-NOT complex subunits affects heart structure and function

29 May 2020

Abstract excerpt

ABSTRACT The identification of genetic variants that predispose individuals to cardiovascular disease and a better understanding of their targets would be highly advantageous. Genome-wide association studies have identified variants that associate with QT-interval length (a measure of myocardial repolarization). Three of the strongest associating variants (single-nucleotide polymorphisms) are located in the...

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PMID: 32471864
DOI: 10.1242/dmm.044727

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