Article

Field–Flow–Front mapping of breast cancer evolutionary dynamics in situ

2026-06-23

Abstract excerpt

Tumour progression reflects not only which clones arise but where, when and in what context they expand—dimensions genotype-centred reconstructions leave unresolved. Here we reconstruct breast cancer evolution in situ across 34 Visium HD, 16 Xenium, 32 MIBI-TOF and 10 CODEX samples, serial-section 3D reconstruction, single-cell and bulk transcriptomes, and genome-wide CRISPR dependency profiles. We partition tumou...

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Literature Corpus work: adedc6b9-aecf-5b91-b92f-c749c21b6447
DOI: 10.64898/2026.06.23.733638

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