Article

The genome-wide analysis of the specification and activation of human chromosomal DNA replication origin sites

2020-01-01

Abstract excerpt

Background: Human DNA replication is a critical cellular process that initiates at tens of thousands of DNA replication origins. Next-generation sequencing (NGS) enabled the elucidation of some characteristics that define human replication origins. Initiation-site sequencing (iniSeq) utilises the established human cell-free system for in vitro DNA replication, whereby a digoxigenin tag is introduced into newly syn...

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Literature Corpus work: 9f29924d-6503-5b21-ad24-3f3802d8b7c4
DOI: 10.17863/cam.72547

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