Article

Transfer learning identifies in vivo senescence heterogeneity and contributions to vascularization and matrix production across species and diverse pathologies

2022-09-20

Abstract excerpt

<title>Abstract</title> Cellular senescence is a state of permanent growth arrest that plays an important role in wound healing, tissue fibrosis, and tumor suppression. Despite senescent cells’ (SnC) pathological role and therapeutic interest, their phenotype in vivo remains poorly defined. Here, we developed an in vivoderived senescence signature using a foreign body response (FBR) fibrosis model in a SnC rep...

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Literature Corpus work: adc5323c-ef36-5662-87e6-79561b2fa0eb
DOI: 10.21203/rs.3.rs-1847932/v1

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