Article

A New Gene Set Identifies Senescent Cells and Predicts Senescence-Associated Pathways Across Tissues

2021-12-13

Abstract excerpt

<title>Abstract</title> <p>Although cellular senescence is increasingly recognized as driving multiple age-related co-morbidities through the senescence-associated secretory phenotype (SASP), in vivo senescent cell identification, particularly in bulk or single cell RNA-sequencing (scRNA-seq) data remains challenging. Here, we generated a novel gene set (SenMayo) and first validated its enrichment in bone biopsie...

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Literature Corpus work: 14e07b6f-ef53-5dd2-8711-9a8bf24c4539
DOI: 10.21203/rs.3.rs-1034608/v1

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