Article

SenSet, a novel human lung senescence cell gene signature, identifies cell-specific senescence mechanisms

2024-12-22

Abstract excerpt

Cellular senescence is a major hallmark of aging. Senescence is defined as an irreversible growth arrest observed when cells are exposed to a variety of stressors including DNA damage, oxidative stress, or nutrient deprivation. While senescence is a well-established driver of aging and age-related diseases, it is a highly heterogeneous process with significant variations across organisms, tissues, and cell types....

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Literature Corpus work: be1a8795-a3fc-51c9-81c1-5d803d92d1af
DOI: 10.1101/2024.12.21.629928

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