Article

Distinct fibroblast and perivascular senotypes define spatial niches that regulate fibrosis

2026-06-10

Abstract excerpt

Fibrotic conditions contribute to significant global morbidity and mortality. Yet the underlying processes that orchestrate fibrosis remain poorly understood due to the cellular and spatial complexity of the stromal, immune, and vascular compartments that regulate fibrotic disease progression. Senescent cells (SnCs) have been implicated in fibrosis, but their roles are unclear, as evidence indicates that they serv...

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Literature Corpus work: 7031a0a1-4e4f-5317-8828-03028a1c42de
DOI: 10.64898/2026.06.08.730636

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