Article

A New Gene Set Identifies Senescent Cells and Predicts Senescence-Associated Pathways Across Tissues

2021-12-11

Abstract excerpt

Although cellular senescence is increasingly recognized as driving multiple age-related co-morbidities through the senescence-associated secretory phenotype (SASP), in vivo senescent cell identification, particularly in bulk or single cell RNA-sequencing (scRNA-seq) data remains challenging. Here, we generated a novel gene set (SenMayo) and first validated its enrichment in bone biopsies from two aged human cohor...

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Literature Corpus work: ec50f188-0c87-565a-81a6-3b70f920652c
DOI: 10.1101/2021.12.10.472095

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