Article
Evaluation of toxicological mechanisms of ochratoxin-A in human primary proximal tubule epithelial cells
2025-09-04
Abstract excerpt
Ochratoxin-A (OTA) is a ubiquitous mycotoxin contaminant in food products and a known nephrotoxin. OTA is hypothesized to be a potential environmental agent causing chronic kidney disease of unknown etiology (CKDu), however the mechanism of OTA toxicity in the human kidney remains elusive. This study aims to elucidate OTA-induced molecular toxicological pathways using primary human proximal tubule epithelial cells...
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Identifiers and source
- Literature Corpus work
- ac774b8d-c9cf-55dd-94cf-3515009e9f2e
- DOI
- 10.1101/2025.08.29.673189
