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Farrerol ameliorated renal fibrosis mediated by mitophagy deficiency in cisplatin-induced chronic kidney disease via Nrf2/PINK1

2024-01-30

Abstract excerpt

<h4>Background: </h4> and Purpose: Mitochondrial dysfunction is essential in renal tubular damage, and mitophagy, a selective form of autophagy, specifically eliminates damaged mitochondria. Mitophagy reportedly protects against diabetic kidney disease, cisplatin-induced acute kidney injury (AKI) and other related kidney diseases, but the specific mechanism by which mitophagy protects against cisplatin-induced chr...

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Literature Corpus work
b2357546-854d-5ce0-ae5a-1282f2327dee
DOI
10.22541/au.170664505.51923178/v1
Open publication

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