Article
Mitochondrial GPX4 acetylation is involved in cadmium-induced renal cell ferroptosis
7 May 2024
Abstract excerpt
Increasing evidences demonstrate that environmental stressors are important inducers of acute kidney injury (AKI). This study aimed to investigate the impact of exposure to Cd, an environmental stressor, on renal cell ferroptosis. Transcriptomics analyses showed that arachidonic acid (ARA) metabolic pathway was disrupted in Cd-exposed mouse kidney. Targeted metabolomics showed that renal oxidized ARA metabolites...
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