Oxidative Stress and Mitochondrial Dysfunction in Chronic Kidney Disease: From Molecular Mechanisms to Biomarkers and Targeted Therapies

Abstract excerpt

Chronic kidney disease (CKD) represents a major global health challenge, affecting more than 10% of the population and contributing substantially to morbidity and premature mortality. Growing evidence identifies oxidative stress and mitochondrial dysfunction as central drivers of renal injury and disease progression across diverse etiologies. The kidney is one of the most mitochondria-rich organs in the body, refl...

Topics

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• Acute Kidney Injury Research
• Adipose Tissue and Metabolism
• Autophagy in Disease and Therapy
• Birth, Development, and Health
• Liver Disease Diagnosis and Treatment
• Metabolism and Genetic Disorders
• Mitochondrial Function and Pathology
• Organ Transplantation Techniques and Outcomes

Identifiers and source

Literature Corpus work

35f4328f-20d9-5e11-982b-891a56653999

DOI

10.20944/preprints202607.1399.v1