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The pathophysiological mechanism of <i>Beni-koji Choleste-Help</i>/puberulic acid-induced kidney injury is proximal tubular mitochondrial dysfunction

2025-06-09

Abstract excerpt

<h4>Introduction</h4> In March 2024, kidney injury, sometimes with Fanconi syndrome, caused by a red yeast rice supplement ( Beni-koji Choleste-Help ), was reported in Japan. By November 24, 2024, 2,628 people had visited medical facilities, making it a social problem. Many patients still show decreased eGFR. However, the previous report only noted that puberulic acid, newly identified for its nephrotoxicity, was...

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Literature Corpus work
770a6aae-51f5-5a6e-a2ba-a122f70b8920
DOI
10.1101/2025.06.08.25329236
Open publication

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