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The MICOS Complex Regulates Mitochondrial Structure and Oxidative Stress During Age-Dependent Structural Deficits in the Kidney

2024-06-10

Abstract excerpt

<h4>ABSTRACT</h4> Due to aging, the efficiency of kidney function begins to decrease. Dysfunction in mitochondria and their cristae is a hallmark of aging. Therefore, age-related decline in kidney function could be attributed to changes in mitochondrial ultrastructure, increased reactive oxygen species, and alterations in metabolism and lipid composition. We sought to understand how mitochondrial ultrastructure i...

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Literature Corpus work
4460e700-ed1b-5b37-a8c9-d6867aef8f34
DOI
10.1101/2024.06.09.598108
Open publication

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The MICOS Complex Regulates Mitochondrial Structure and Oxidative Stress During Age-Dependent Structural Deficits in the KidneyDOI 10.1101/2024.06.09.598108
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