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Through its genoprotective, mitochondrial bioenergetic modulation, and antioxidant effects, Fucoxanthin and its metabolite minimize Ochratoxin A-induced nephrotoxicity in HK-2 human kidney cells

2025-04-22

Abstract excerpt

<title>Abstract</title> <p>Background Ochratoxin A (OTA) is a mycotoxin with reported multiorgan toxicity, especially kidney toxicity. Fucoxanthin (FX) and its hydrolyzed metabolite Fucoxanthinol (FXL) have reno-protective antioxidant and anti-inflammatory properties. This study evaluates the nephroprotective effects of FX and FLX on OTA-induced renal cytotoxicity using the HK-2 cell line. Methods Molecular doc...

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Literature Corpus work
fee0a90c-f760-594d-898f-7e5dc357f419
DOI
10.21203/rs.3.rs-6077785/v1
Open publication

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Through its genoprotective, mitochondrial bioenergetic modulation, and antioxidant effects, Fucoxanthin and its metabolite minimize Ochratoxin A-induced nephrotoxicity in HK-2 human kidney cellsDOI 10.21203/rs.3.rs-6077785/v1
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