Article

Meiotic and mitotic aneuploidies drive arrest of in vitro fertilized human preimplantation embryos

2022-07-03

Abstract excerpt

The high incidence of aneuploidy in early human development, arising either from errors in meiosis or postzygotic mitosis, is the primary cause of pregnancy loss, miscarriage, and still birth following natural conception as well as in vitro fertilization (IVF). Preimplantation genetic testing for aneuploidy (PGT-A) has confirmed the prevalence of meiotic and mitotic aneuploidies among blastocyst-stage IVF embryos...

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Literature Corpus work: ac756e9d-4a28-5dbe-bb43-0784d6e25113
DOI: 10.1101/2022.07.03.498614

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