Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Prediction model for aneuploidy in early human embryo development revealed by single-cell analysis

7 Jul 2015

Abstract excerpt

Aneuploidies are prevalent in the human embryo and impair proper development, leading to cell cycle arrest. Recent advances in imaging and molecular and genetic analyses are postulated as promising strategies to unveil the mechanisms involved in aneuploidy generation. Here we combine time-lapse, complete chromosomal assessment and single-cell RT-qPCR to simultaneously obtain information from all cells that...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Pluripotent Stem Cells Research
Share to Prenatal Screening and Diagnostics
Share to Renal and related cancers

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Source

Identifiers

PMID: 26151134
DOI: 10.1038/ncomms8601

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 8 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Prediction model for aneuploidy in early human embryo development revealed by single-cell analysisPMID 26151134Read ↗

Single-cell Transcriptomics of Postimplantation Embryos: Unveiling Aneuploidy Effects and Lineage DynamicsSemantic proximity Read ↗

A multi-omics genome-and-transcriptome single-cell atlas of human preimplantation embryogenesis reveals the cellular and molecular impact of chromosome instabilitySemantic proximity Read ↗

Single-cell analysis of human embryos reveals diverse patterns of aneuploidy and mosaicism.Semantic proximity Read ↗

Dynamic blastomere behaviour reflects human embryo ploidy by the four-cell stageSemantic proximity Read ↗

Single-cell analysis of human embryos reveals diverse patterns of aneuploidy and mosaicismSemantic proximity Read ↗

Mouse model of chromosome mosaicism reveals lineage-specific depletion of aneuploid cells and normal developmental potentialSemantic proximity Read ↗

Mosaic results after preimplantation genetic testing for aneuploidy may be accompanied by changes in global gene expressionSemantic proximity Read ↗

Aneuploidy and early human embryo developmentSemantic proximity Read ↗

Human embryos harbor complex mosaicism with broad presence of aneuploid cells during early developmentSemantic proximity Read ↗

Morphokinetic behavior of euploid and aneuploid embryos analyzed by time-lapse in embryoscopeSemantic proximity Read ↗

Meiotic and mitotic aneuploidies drive arrest of in vitro fertilized human preimplantation embryosSemantic proximity Read ↗

Aneuploidy is a key causal factor of delays in blastulation: author response to ‘A cautionary note against aneuploidy risk assessment using time-lapse imaging’Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.