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Aneuploidy and early human embryo development

15 Apr 2008

Abstract excerpt

Human embryo development occurs through a process that encompasses reprogramming, sequential cleavage divisions and mitotic chromosome segregation and embryonic genome activation. Chromosomal abnormalities may arise during germ cell and/or pre-implantation embryo development, and are a major cause of spontaneous miscarriage or birth defects. Nonetheless, model systems suitable for the study of human germ cell and...

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PMID: 18632690
DOI: 10.1093/hmg/ddn170

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